Severe acute respiratory syndrome (SARS): epidemiology and clinical features
Identifieur interne : 001475 ( Pmc/Checkpoint ); précédent : 001474; suivant : 001476Severe acute respiratory syndrome (SARS): epidemiology and clinical features
Auteurs : D. Hui ; M. Chan ; A. Wu ; P. NgSource :
- Postgraduate Medical Journal [ 0032-5473 ] ; 2004.
Abstract
Severe acute respiratory syndrome (SARS) is a newly emerged infectious disease with a significant morbidity and mortality. The major clinical features include persistent fever, chills/rigor, myalgia, malaise, dry cough, headache, and dyspnoea. Older subjects may present without the typical febrile response. Common laboratory features include lymphopenia, thrombocytopenia, raised alanine transaminases, lactate dehydrogenase, and creatine kinase. The constellation of compatible clinical and laboratory findings, together with certain characteristic radiological features and lack of clinical response to broad spectrum antibiotics, should arouse suspicion of SARS. Measurement of serum RNA by real time reverse transcriptase-polymerase chain reaction technique has a detection rate of 75%–80% in the first week of the illness.
Url:
DOI: 10.1136/pgmj.2004.020263
PubMed: 15254300
PubMed Central: 1743054
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:1743054Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Severe acute respiratory syndrome (SARS): epidemiology and clinical features</title><author><name sortKey="Hui, D" sort="Hui, D" uniqKey="Hui D" first="D" last="Hui">D. Hui</name></author><author><name sortKey="Chan, M" sort="Chan, M" uniqKey="Chan M" first="M" last="Chan">M. Chan</name></author><author><name sortKey="Wu, A" sort="Wu, A" uniqKey="Wu A" first="A" last="Wu">A. Wu</name></author><author><name sortKey="Ng, P" sort="Ng, P" uniqKey="Ng P" first="P" last="Ng">P. Ng</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">15254300</idno><idno type="pmc">1743054</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1743054</idno><idno type="RBID">PMC:1743054</idno><idno type="doi">10.1136/pgmj.2004.020263</idno><date when="2004">2004</date><idno type="wicri:Area/Pmc/Corpus">001962</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001962</idno><idno type="wicri:Area/Pmc/Curation">001962</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001962</idno><idno type="wicri:Area/Pmc/Checkpoint">001475</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001475</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Severe acute respiratory syndrome (SARS): epidemiology and clinical features</title><author><name sortKey="Hui, D" sort="Hui, D" uniqKey="Hui D" first="D" last="Hui">D. Hui</name></author><author><name sortKey="Chan, M" sort="Chan, M" uniqKey="Chan M" first="M" last="Chan">M. Chan</name></author><author><name sortKey="Wu, A" sort="Wu, A" uniqKey="Wu A" first="A" last="Wu">A. Wu</name></author><author><name sortKey="Ng, P" sort="Ng, P" uniqKey="Ng P" first="P" last="Ng">P. Ng</name></author></analytic><series><title level="j">Postgraduate Medical Journal</title><idno type="ISSN">0032-5473</idno><idno type="eISSN">1469-0756</idno><imprint><date when="2004">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p> Severe acute respiratory syndrome (SARS) is a newly emerged infectious disease with a significant morbidity and mortality. The major clinical features include persistent fever, chills/rigor, myalgia, malaise, dry cough, headache, and dyspnoea. Older subjects may present without the typical febrile response. Common laboratory features include lymphopenia, thrombocytopenia, raised alanine transaminases, lactate dehydrogenase, and creatine kinase. The constellation of compatible clinical and laboratory findings, together with certain characteristic radiological features and lack of clinical response to broad spectrum antibiotics, should arouse suspicion of SARS. Measurement of serum RNA by real time reverse transcriptase-polymerase chain reaction technique has a detection rate of 75%–80% in the first week of the illness. </p></div></front></TEI><pmc xml:lang="EN" article-type="review-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Postgrad Med J</journal-id><journal-title>Postgraduate Medical Journal</journal-title><issn pub-type="ppub">0032-5473</issn><issn pub-type="epub">1469-0756</issn><publisher><publisher-name>BMJ Group</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">15254300</article-id><article-id pub-id-type="pmc">1743054</article-id><article-id pub-id-type="doi">10.1136/pgmj.2004.020263</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Severe acute respiratory syndrome (SARS): epidemiology and clinical features</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Hui</surname><given-names>D</given-names></name></contrib><contrib contrib-type="author"><name><surname>Chan</surname><given-names>M</given-names></name></contrib><contrib contrib-type="author"><name><surname>Wu</surname><given-names>A</given-names></name></contrib><contrib contrib-type="author"><name><surname>Ng</surname><given-names>P</given-names></name></contrib></contrib-group><aff>Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong.<email>dschui@cuhk.edu.hk</email></aff><pub-date pub-type="ppub"><month>7</month><year>2004</year></pub-date><volume>80</volume><issue>945</issue><fpage>373</fpage><lpage>381</lpage><self-uri xlink:role="pdf" xlink:type="simple" xlink:href="http://pmj.bmj.com/cgi/reprint/80/945/373.pdf"></self-uri><self-uri xlink:role="abstract" xlink:type="simple" xlink:href="http://pmj.bmj.com/cgi/content/abstract/80/945/373"></self-uri><self-uri xlink:role="fulltext" xlink:type="simple" xlink:href="http://pmj.bmj.com/cgi/content/full/80/945/373"></self-uri><abstract><p> Severe acute respiratory syndrome (SARS) is a newly emerged infectious disease with a significant morbidity and mortality. The major clinical features include persistent fever, chills/rigor, myalgia, malaise, dry cough, headache, and dyspnoea. Older subjects may present without the typical febrile response. Common laboratory features include lymphopenia, thrombocytopenia, raised alanine transaminases, lactate dehydrogenase, and creatine kinase. The constellation of compatible clinical and laboratory findings, together with certain characteristic radiological features and lack of clinical response to broad spectrum antibiotics, should arouse suspicion of SARS. Measurement of serum RNA by real time reverse transcriptase-polymerase chain reaction technique has a detection rate of 75%–80% in the first week of the illness. </p></abstract></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Chan, M" sort="Chan, M" uniqKey="Chan M" first="M" last="Chan">M. Chan</name><name sortKey="Hui, D" sort="Hui, D" uniqKey="Hui D" first="D" last="Hui">D. Hui</name><name sortKey="Ng, P" sort="Ng, P" uniqKey="Ng P" first="P" last="Ng">P. Ng</name><name sortKey="Wu, A" sort="Wu, A" uniqKey="Wu A" first="A" last="Wu">A. Wu</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Pmc/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001475 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 001475 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Pmc
|étape= Checkpoint
|type= RBID
|clé= PMC:1743054
|texte= Severe acute respiratory syndrome (SARS): epidemiology and clinical features
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:15254300" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |